The Bills are one of the league's most generous passing defenses, but they also give up a ton of yards on the ground. I think the Patriots will try to grind out a win with a balanced attack on offense, and that means a lot of Green-Ellis and Woodhead. Still, I could easily foresee Brady bouncing back from an "off" week last week with 280 yards and 2-3 scores.
Wes Welker/Deion Branch
The Pats' top two WRs were held to just 5 total catches last week, but I don't expect that to be the case this weekend. The Bills typically limit the yardage totals of opposing wideouts, but the New England WR corps is anything but typical. Look for both players to post similar statlines around 4-6 catches for 80-100 yards and a good chance of a score. I'd start either guy as a #2 WR with confidence.
BenJarvus Green-Ellis/Danny Woodhead
Patriot running backs should bring a sleigh full of goodies on Christmas weekend against Buffalo's 32nd ranked defense. Both of these guys could crack the top 10 or 15 in running back scoring this week. I'm betting that both players will end up with 75+ yards and a score.
Rob Gronkowski/Aaron Hernandez
While Hernandez scored twice last week, Gronkowski is still getting the bulk of the playing time. The Bills allow the 7th-most fantasy points to tight ends, so I think either guy is worth a start. If you're deciding between both players, I'd still lean toward Gronkowski.
Patriots Defense/Special Teams
While the Buffalo offense is nothing to write home about, Fitzpatrick has been doing a decent job of getting the ball out of his hands quickly and limiting mistakes. In his last four games, he's taken just 7 sacks. Although he has fumbled four times during that span, I'm not sure that is a trend we can hang our hat on. This unit is no better than a fringe starting option this week.